Endocrine Abstracts

Introduction: During adrenal insufficiency (AI), glucocorticoid treatment is supposed to be neutral on the metabolic parameters of patients. However, recent data from the literature report that this corticosteroid replacement therapy increases the metabolic risk. The aim of our work was to determine the metabolic and cardiovascular impact of hydrocortisone (HC) replacement therapy during peripheral AI.Patients and methods: This was a descriptive and anal...

Introduction: Hydrocortisone (HC) is the most widely used replacement molecule in the treatment of adrenal insufficiency (AI). This substitution treatment is far from ideal especially as it is impossible to reproduce the nycthemeral cycle of cortisol with its current galenic form which has a short half-life. The aim of our work was to determine the impact of HC treatment of peripheral AI on the long-term quality of life and sleep.Patients and methods: Th...

Introduction: The treatment of adrenal insufficiency (AI) is based on long-term glucocorticoid substitution. Hydrocortisone (HC) is the most commonly used substitution molecule. The aim of our work was to determine the long-term bone impact of patients with peripheral AI.Patients and methods: This is a descriptive and analytical study involving 77 patients with peripheral IS (66 women and 11 men), all treated with HC. For each patient, we determined the ...

Introduction: Diabetes mellitus (DM) and depression are two frequent health conditions. Their coexistence may represent a medical challenge for clinicians. In addition, early detection of depression can help in better management of diabetes and preventing its complications.Aim of the study: To assess depression and glycemic control among a group of patients having diabetes.Methods: A cross sectional study was conducted among diabet...

Introduction: Diabetes distress (DD) refers to the emotional burdens and worries, often hidden, that are part of the spectrum of the patient experience when managing a chronic and demanding disease like diabetes. The objective of this work was to determine the prevalence of DD and its clinical determinants in type 2 diabetic patients.Patients and methods: Cross-sectional study conducted on 92 type 2 diabetic patients who consulted on an outpatient basis ...

Introduction: Medication Adherence (MA) is the extent to which patients follow medical instructions. Poor MA is frequently encountered in the majority of chronic diseases, including diabetes. The aim of our study was to evaluate MA in patients with poorly controlled type 2 diabetes mellitus (T2DM).Patients and methods: We conducted a cross-sectional study over a period of 2 months, including patients with poorly controlled T2DM, followed at the endocrino...

Introduction: Glycemic control in elderly diabetics is a challenge. Treatment Satisfaction reflects this control.Objectives: To assess insulin treatment satisfaction and to determine the factors associated with insulin treatment satisfaction among type 2 diabetic elderly.Methods: A cross-sectional study on 86 type 2 diabetic insulin dependent elderly recruited from the outpatient endocrinology consultation during June and July 2021...

Introduction: Acromegaly is a rare hormonal condition that results from an excess amount of growth hormone (GH) in the body. A variety of complications have been reported in patients with acromegaly including cardiovascular diseases, diabetes mellitus or respiratory disorders. In addition, Acromegaly is associated with gastrointestinal complications. The aim of this study was to evaluate gastrointestinal complications and their impact on the quality of life among patients suff...

Introduction: Thyroid diseases have been known to cause haemostatic changes, either tendency to bleeding or thrombosis. We report a case of a patient with primary hypothyroidism presenting with spontaneous bleeding and jugular thrombosis.Case report: An 85-year old patient with no medical history was admitted to the endocrinology department with primary auto-immune hypothyroidism. Hypothyroidism was suspected because of severe loss of weight and appetite...

Introduction: Thyroid hormones in fluence kidney function and thereby might alter serum urate levels, a major risk factor for gouty arthritis. Previous research documented a high prevalence of elevated levels of Uric acid in primary hypothyroid patients. We present the case of an incident gout attack in a patient with primary hypothyroidism.Case report: A 72-year-old male was hospitalized for a primary hypothyroidism complicated by a rhabdomyolysis. Labo...